Following recent investments by the Bill & Melinda Gates Foundation and others for improved STH control, the Neglected Infectious Disease (NID) team asked the START team to seek out and evaluate data to support key strategic questions that will be important in determining if targets for sustained control and/or elimination can be met with existing tools. The NID team tasked START with three objectives:
- Objective 1: Conduct a landscape analysis of prior deworming efforts where successful elimination has been achieved. If possible, compare methods, tools, and policy used in successful eliminations to those used in countries in which successful elimination has not occurred.
- Objective 2: Summarize and evaluate data available for the impact of WASH interventions, examining the metrics used and identifying key gaps that will need to be addressed to maximize WASH interventions for the sustained control and/or elimination of STH.
- Objective 3: Determine strategies utilized in animal husbandry and veterinary practice to mitigate the risk of drug resistance among animals receiving routine empiric treatment to control STH.
The START team unearthed and explored archival data from the Southern USA, Japan, and Korea STH elimination campaigns. A summary and critique of the evidence for WASH interventions was prepared and presented. The START team worked with Guy Palmer, Director of the Paul G. Allen School of Global Animal Health, to finalize an evaluation of the history and risk of anthelminthic drug resistance in both animals and humans and how strategies for resistance prevention used in the treatment of animals can be translated and applied to the treatment of human populations. Final deliverables included a report for each objective and accompanying slide deck.